Here is a relaxed and rewarding way to spend 48 hours in Panama City.
Day One: History and the Panama Canal
Morning – Visit the Panama Canal
Begin your first day at one of the world’s most famous landmarks: the Panama Canal. Watching ships navigate the Miraflores Locks is one of the most fascinating experiences in Panama.
Standing beside the locks gives visitors a close-up look at how this engineering marvel operates and why it remains one of the most important waterways on earth.
Afternoon – Explore Casco Viejo
Next, head to Casco Viejo, the historic district founded in 1673 after the original city was destroyed by pirates.
Today the neighborhood is full of restored buildings, quiet plazas, boutique hotels, and cafés. It’s a wonderful place to explore slowly, camera in hand, discovering hidden courtyards and beautiful colonial architecture.
Evening – Sunset on the Waterfront
End the day along the Cinta Costera, where locals gather along the waterfront park that curves around the bay. From here you’ll see one of the most dramatic skylines in Latin America.
Day Two: Views, Nature, and the Modern City
Morning – The Amador Causeway
Start your second day with a drive or walk along the Amador Causeway, a scenic stretch connecting several small islands at the entrance to the Panama Canal.
The views here are spectacular, with the city skyline on one side and ships waiting to enter the canal on the other.
Midday – Museums and Local Food
The causeway is also home to the Biomuseo, a striking museum designed by architect Frank Gehry that tells the story of Panama’s incredible biodiversity.
Nearby restaurants offer fresh seafood and relaxed ocean views.
Afternoon – Discover the Modern Skyline
Finish your trip by exploring Panama City’s modern districts such as Punta Paitilla, Obarrio, and Avenida Balboa, where gleaming skyscrapers rise along the Pacific coast.
It’s a reminder that Panama City is not only historic — it’s also one of the most dynamic cities in Latin America.
Book now and live the experience.